Description
Ciprofloxacin belongs to the group of quinolones and acts bactericidally against mainly Gramnegative bacteria, like Campylobacter spp., E. coli, Haemophilus spp., Mycoplasma spp., Pasteurella spp. and Salmonella spp. Ciprofloxacin is a fluoroquinolone derivative in veterinary medicine with outstanding antibacterial activity primarily against Gram-negative pathogens, but also Gram-positive bacteria and some Chlamydia, Mycoplasma, and many Mycobacterium species. Therefore, Ciprofloxacin is used as a potential therapeutic application for many types of infection. Ciprofloxacin has bactericidal activity. It acts by inhibiting bacterial DNA synthesis by binding to and inhibiting the action of DNA gyrase, or topoisomerase IV, enzymes responsible for mediating the supercoiling of DNA in DNA replication. Ciprofloxacin stops the multiplication of bacteria by inhibiting the reproduction and repair of their genetic material (DNA).