GLUCOSAMINE AND CHONDROITINE – necessary for the synthesis of extracellular matrix which form the structural basis for articular cartilages. Ensure the proper hydration of articular cartilages, guaranteeing their resilience and elasticity.

HARPAGOPHYTUM PROCUMBENS – shows anti-inflammatory properties, probably due to the inhibition of the activity of enzymes such as cyclooxygenase and lipoxygenase.

DRY AVOCADO, SOY EXTRACT – show anabolic, anticatabolic, and anti-in-flammatory effects on chondrocytes; in-crease collagen synthesis; inhibit the 1-beta interleukin induced collagenase; boost the synthesis of aggrecan; inhibit the IL1β-de-pendent activation of extracellular matrix metalloproteineases (MMP)-3, IL-6, IL-8 and prostaglandin E2 (PGE2).

MANGANESE – serves as a building block of enzyme molecules known as glycosyltransferases, necessary for the synthesis of proteoglycans that ensure healthy bones and cartilages.

Instruction for proper use:

1 tablet per 20 kg b.w. daily.
Administered before or during meals.
Tablets can be administered crushed.
If daily dose provides administration of several tablets it can be divided into 2-3 portions.
Animals should always have access to fresh water.

Composition: 13.2.8 glucosamine from animal tissues, 13.1.7 dried avocado Persea americana Mill., 2.18.11 soya beans Glycine max. L. Merr., 13.12.2 chondroitin sulphate, 13.6.4 magnesium stearate, 11.4.7 sodium hyaluronate, 13.6.6 stearic acid.

Nutritional additives (g/kg): 3a911 L-carnitine L-tartrate 46.5 g, 3a300 vitamin C 26.3 g, 3b502 manganese (II) oxide 1.8 g, 3b603 zinc oxide 1.3 g.

Sensory additives (g/kg): 2b Devil’s claw Harpagophytum procumbens extract 10.5 g.

Technological additives (g/kg): 1E460 microcrystalline cellulose 232.5 g, 1E551b colloidal silica 5.3 g.

Frontline – Spot On Dog – 2 up to 10 kg

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